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DigiNerve Focus Series - Hematology Pathology

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Q1. A 58-year-old male with chronic kidney disease and osteoarthritis presents with mild pallor and fatigue. Lab investigations reveal Hb 10 g/dL, MCV 87 fL, serum iron 45 µg/dL (low), serum ferritin 200 ng/mL (normal-high), and TIBC 210 µg/dL (low). CRP is elevated.

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Q2. Identify the diagnosis.

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Q3. A 62-year-old male presented with fatigue and dark-colored urine. Lab tests revealed: Hemoglobin: 8.9 g/dL, Reticulocyte count: elevated, Serum LDH: high, Indirect bilirubin: elevated, Urine: positive for hemoglobin. Peripheral smear is shown below:

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Q4. A 68-year-old patient presented with easy fatiguability, weight loss. The WBC showed WBC 85.000/ μL, peripheral lymphocytosis. His bone marrow reveals the given picture. Identify the diagnosis.

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Q5. Peripheral smear of 35-year-old male with fatigue & mucosal bleeding revealed abnormal promyelocytes with bundles of Auer rods (faggot cells) with pancytopenia. Coagulation profile shows prolonged PT & low fibrinogen. Which chromosomal translocation is most likely responsible for this condition?

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Q6. Hyperdiploidy more than 50 chromosomes is seen in:

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Q7. All the following are incorrect for Hereditary Spherocytosis EXCEPT

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Q8. The following picture shows a lymph nodes biopsy of a 30-year-old male with cervical lymphadenopathy. The diagnosis is:

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Q9. Which statement is NOT TRUE about von Willebrand disease?

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Q10. Which of the following is true for lavender top vacutainer?

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